Scientifically proven

Extensive preclinical studies in 2008 demonstrated the positive properties of the ceramic.implant. As a result, a multicenter clinical study was prepared at the Universities of Freiburg and Zurich and implemented from 2009 onwards.

Numerous studies make ceramicimplant one of the best documented ceramic implants ever.

Numerous other studies make ceramic.implant one of the best documented ceramic implants ever.


The study results prove:

  • Success with single-tooth replacement and fixed partial dentures 204), 237)

  • Fast and safe healing 46), 201), 243)

  • Healing possible without protective splint 201)

  • Soft tissue behavior is analogous to natural teeth 201), 224), 243)

  • Improved cell maturation of osteoblasts 242)

  • Stable bone level 201), 243)

Documentation Summary III

Documentation Summary III is a DEKRA-certified literature study about implants (comparison of titanium and zirconia) and all-ceramic restorations commissioned by PROSEC. It summarizes the studies on VITA Zahnfabrik and vitaclinical products in 272 pages.

Documentation Summary III is a literature study about implants and all-ceramic restorations commissioned by PROSEC

It outlines the relevant studies of the last five years and serves as a scientific basis for future changes. The following conclusions can be drawn:

  • Long-term studies show that one-piece zirconia implants with a reworked surface have proven to be excellent.

  • Teeth and implants can be successfully restored with monolithic ceramics (lithium disilicate, zirconia).

  • Before two-piece zirconia implants can be recommended for daily use in practices, clinical data must be available over a longer period of time.

The Documentation Summary III, with over 200 relevant studies, can be ordered at


Numbering references the page number in Documentation Summary III.

33) Bergemann C, Duske K, Nebe JB, Schöne A, Bulnheim U, Seitz H, Fischer J. Microstructured dental zirconia surfaces modulate osteogenic marker genes in human primary osteoblasts. J Mater Sci Mater Med. 2015 Jan;26(1):5350.

46) Thoma DS, Benic GI, Muñoz F, Kohal R, Sanz Martin I, Cantalapiedra AG, Hämmerle CHF, Jung RE. Histological analysis of loaded zirconia and titanium dental implants: an experimental study in the dog mandible. J Clin Periodontal. 2015 Oct;42(10):967– 975.

91) Fischer J, Schott A, Märtin S. Surface micro-structuring of zirconia dental implants. Clin Oral Implants Res. 2016 Feb;27(2):162-166.

126) Just BA, Schöne A, Fischer J. Effect of the design on the strength of ceramic implants. IADR/AMER General Session & Exhibition Cape Town, South Africa June 25-28, 2014.

201) Jung RE, Grohmann P, Sailer I, Steinhart YN, Fehér A, Hämmerle C, Strub JR, Kohal R. Evaluation of a one-piece ceramic implant used for single-tooth replacement and three-unit fixed partial dentures: a prospective cohort clinical trial. Clin Oral Implants Res. 2015 Jul 27.(7):751-761.

204) Spies B, Kohal R, Balmer M, Vach K, Jung R. Evaluation of zirconia-based posterior single crowns supported by zirconia implants: Preliminary results of a prospective multicenter study. Clin Oral Implants Res. 2017 May;28(5):613-619.

218) Wenz HJ, Bartsch J, Wolfart S, Kern M. Osseointegration and clinical success of zirconia dental implants: a systematic review. Int J Prosthodont. 2008 Jan-Feb;21(1):27- 36.

224) Weng D. Zirkonoxid und periimplantäres Weichgewebe. Eine klinische Beobachtung. Implantologie 2014;22 (1):65-70.

237) Pieralli S, Kohal RJ, Jung RE, Vach K, Spies BC. Clinical outcomes of zirconia dental implants: A systematic review. J Dent Res. 2017 Jan;96(1):38-46.

242) Duske K, Nebe B, Schöne A, Bergemann C, Fischer J. Microstructured dental zirconia surfaces stimulate gene expression and cell adhesion of human primary osteoblasts. Conference Paper Euopean Conferene for Osseointegration, 2014, September 25-27, Rome, Italy.

Submitted for Documentation Summary IV.

243) Balmer M, Spies BC, Vach K, Kohal RJ, Hämmerle CHF, Jung RE. Three-year analysis of zirconia implants used for single-tooth replacement and three-unit fixed dental prostheses: A prospective multicenter study. Clin Oral Implants Res. 2018 Mar;29(3):290-299.

244) Hämmerle CHF, Jung RE, Balmer M. Report on clinical and radiological outcomes of a one-piece zirconia implant system – 5 years-result of a prospective clinical trial; extended abstract.

245) Internal (VITA R&D) and external flexural strength measurements according to DIN EN ISO 6872 and ISO 13356.